AI external control arms

De-risk early-stage clinical trials

Owkin's external control arms increase the probability of success of your trial by providing early efficacy information

Question

How do we improve efficacy information in early-stage trials?

Providing a comparator arm in single arm phase I/II trials prevents late stage trial failures.
By increasing scientific and clinical accuracy, we help biopharma improve investor and regulatory perception of their assets.

Owkin’s solution 

AI external control arms

Owkin's AI external control arms provide early estimates of efficacy for single-arm phase I/II clinical trials to reduce phase II/III uncertainty.

Methodology

Click
Next
Step 1
1
Analyze
phase I/II single arm trial data
Down
Extract key information on inclusion criteria and important patient clinical data
Step 1
Analyze
single arm trial data
Click
Next
Step 2
2
Data hunt
for external multimodal data
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Accurately matching the trial population with the disease and standard of care
Step 2
Data hunt
for external multimodal data
Click
Next
Step 3
3
State-of-the-art ML
Down
To train a model to predict treatment effect based on propensity score, G-computation or DDML
Step 3
State-of-the-art ML
to train a model
Click
Next
Output
Output
Comparison
between patient outcome and predicted outcome
Down
Improved efficacy analysis
Output
Comparison
between outcomes

AI External Control Arms

Why Owkin?

Multimodal data access icon
Multimodal data access

We access hard-to-find data to accurately match your inclusion criteria.

AI & scientific expertise icon
AI & scientific expertise 

Renowned AI expertise with # published papers in leading journals, two strategic alliances with leading biopharma companies, and AI digital pathology diagnostics.

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Federated technologies

We can federate siloed data to increase the size and diversity of datasets.

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Regulatory

Continued conversations with regulators plus ongoing projects with Pharma that include regulatory discussions.

Get in touch