Rewiring Biology
A two-day hackathon where frontier engineers, AI scientists, and computational biologists build the tools that help science move faster.

How can frontier AI systems reason and act over complex biological data to support real scientific discovery?
Background
Biology is generating data faster than science can interpret it. Spatial omics, genomics, imaging, and literature are accumulating at a pace no human — or conventional tool — can keep up with.
Owkin has spent years building infrastructure and datasets at the intersection of AI and biomedical research. Combined with K Pro, Owkin’s AI Scientist, this creates a rare opportunity to explore how AI can genuinely accelerate the pace of biomedical discovery.
Challenge
In this hackathon, participants will build MCP tools and agentic components that extend what an AI Scientist can already do: reasoning over biological data, forming hypotheses, mapping context, and surfacing insights and semi-autonomously explore research spaces that would otherwise take weeks of manual work.
What you will build
MCP tools and agents that can be integrated in the future into K Pro
Workflows that combine MOSAIC Window spatial omics data with public literature and biomedical knowledge bases
Tool-using or multi-agent systems designed for research-style reasoning and analysis
New capabilities that improve biologically grounded hypothesis generation and scientific question answering
Hackathon day 1
July 10, 2026
Introductory and plenary sessions followed by the official hackathon kick-off.
Hackathon day 2
July 11, 2026
Project pitches, winner announcements and closing ceremony with guest speaker and entertainment.
Participants will receive access to:
- K Pro
Owkin’s AI Scientist for biomedical reasoning, experimentation and exploration of public literature and databases - MOSAIC Window
A curated public data tier derived from Owkin’s proprietary dataset MOSAIC, the world’s largest spatial omics dataset in oncology - TCGA
The Cancer Genome Atlas, a comprehensive public genomic and clinical dataset - You.com credits
for AI-powered search and retrieval augmentation - Claude API credits
for model development, reasoning, and experimentation
How can an AI Scientist tighten the cycle between computational hypothesis and wet-lab experiment? Build tools and workflows that help researchers prioritise, design, or interpret experiments more efficiently.
Biological knowledge has no shared map. Build tools that help an AI Scientist bootstrap context from a research question, traverse and enrich it mid-experiment, and consolidate findings into a persistent knowledge structure it can reason over across sessions.
Given a domain, a dataset, or a scientific question, what hypotheses are worth testing? Build agents that can reason from data and literature to propose novel, testable directions.
Research cycles are slow. Build tools that compress the time between question and answer, whether through smarter search, faster analysis, or better synthesis of existing evidence.
MOSAIC Window and TCGA provide rich, complementary data modalities. Build agents capable of reasoning jointly across spatial omics, gene expression, and clinical annotations to surface biological insights.
Projects will compete across two prize tracks
Awarded to the most compelling and reusable AI capability built with K Pro or the provided datasets.
- Integrability
- Performance
- Depth of biomedical reasoning
- Extension of K Pro capabilities
- Usefulness and reusability
- Technical quality and user experience
Awarded to the most ambitious but functional project, recognising teams that swung for something genuinely new, even if not fully finished.
- Ambition and originality
- Performance vs. function
- Novel interaction paradigms
- Long-term potential
- “This feels like the future” factor
Who should apply?
You might come from the building side — agentic components, AI workflows, LLM-based reasoning systems, scientific tooling and research infrastructure.
Or from the biology side — computational biology and bioinformatics, from single-cell and spatial omics to biomedical imaging and multimodal data.
The best teams bring both.
- ML researchers and AI scientists
- Agent builders and frontier engineers
- Computational biologists and bioinformaticians
- Research engineers with a product sensibility

