Rewiring Biology Hackathon
Gradient K Stripe

Rewiring Biology

Biology runs on connections. We're building new ones.

A two-day hackathon where frontier engineers, AI scientists, and computational biologists build the tools that help science move faster.

Apply to participate
An Owkin Hackathon
Date: July 10 - July 11, 2026
Venue: Trellis Coworking & Events
Location: 981 Mission Street, San Francisco, CA 94103, United States
See the venue
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Consulting doctors
The Challenge

How can frontier AI systems reason and act over complex biological data to support real scientific discovery?

Background

Biology is generating data faster than science can interpret it. Spatial omics, genomics, imaging, and literature are accumulating at a pace no human — or conventional tool — can keep up with.

Owkin has spent years building infrastructure and datasets at the intersection of AI and biomedical research. Combined with K Pro, Owkin’s AI Scientist, this creates a rare opportunity to explore how AI can genuinely accelerate the pace of biomedical discovery.

Challenge

In this hackathon, participants will build MCP tools and agentic components that extend what an AI Scientist can already do: reasoning over biological data, forming hypotheses, mapping context, and surfacing insights and semi-autonomously explore research spaces that would otherwise take weeks of manual work.

Challenge themes
More about MCPs
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Structure

What you will build

Participants will develop MCP tools, agents, and workflows that extend the capabilities of AI scientist systems like K Pro. Submissions may take the form of MCP tools, agentic components and any other relevant materials.
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MCP tools and agents that can be integrated in the future into K Pro

MOSAIC Icon

Workflows that combine MOSAIC Window spatial omics data with public literature and biomedical knowledge bases

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Tool-using or multi-agent systems designed for research-style reasoning and analysis

Data search icon

New capabilities that improve biologically grounded hypothesis generation and scientific question answering

Preliminary programme

Hackathon day 1

July 10, 2026

Introductory and plenary sessions followed by the official hackathon kick-off.

Hackathon day 2

July 11, 2026

Project pitches, winner announcements and closing ceremony with guest speaker and entertainment.

Resources

Participants will receive access to:

  • K Pro
    Owkin’s AI Scientist for biomedical reasoning, experimentation and exploration of public literature and databases
  • MOSAIC Window
    A curated public data tier derived from Owkin’s proprietary dataset MOSAIC, the world’s largest spatial omics dataset in oncology
  • TCGA
    The Cancer Genome Atlas, a comprehensive public genomic and clinical dataset
  • You.com credits
    for AI-powered search and retrieval augmentation
  • Claude API credits
    for model development, reasoning, and experimentation
Challenge Themes
The following open problems in AI-native biomedical research are particularly interesting to us. Teams are not required to address one of these themes exclusively, but the strongest submissions will connect to at least one of these frontiers:
Lab in the Loop Icon
Optimize lab-in-the-loop
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Knowledge graphs for biological context mapping
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AI-driven hypothesis generation
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Accelerating experimental cycle time
Multimodal Data Icon
Multimodal reasoning over spatial and genomic data
Prizes

Projects will compete across two prize tracks

Prizes are designed to be meaningful for serious builders: winning tools will be considered for direct integration into K Pro, Owkin’s production AI Scientist environment.
Best AI Scientist MCP Award
Performance over function
Best AI Scientist MCP

Awarded to the most compelling and reusable AI capability built with K Pro or the provided datasets.

Judging criteria:
  • Integrability
  • Performance
  • Depth of biomedical reasoning
  • Extension of K Pro capabilities
  • Usefulness and reusability
  • Technical quality and user experience
Frontier Award
Ambition over implementation
Frontier Award

Awarded to the most ambitious but functional project, recognising teams that swung for something genuinely new, even if not fully finished.

Judging criteria:
  • Ambition and originality
  • Performance vs. function
  • Novel interaction paradigms
  • Long-term potential
  • “This feels like the future” factor
registration

Who should apply?

We are selecting up to 50 participants to form interdisciplinary teams of 2–5 people. The strongest teams will combine expertise across AI systems, biology, reasoning workflows, and product thinking.
Relevant experience & background

You might come from the building side — agentic components, AI workflows, LLM-based reasoning systems, scientific tooling and research infrastructure.

Or from the biology side — computational biology and bioinformatics, from single-cell and spatial omics to biomedical imaging and multimodal data.

The best teams bring both.

An Owkin Hackathon
  • ML researchers and AI scientists
  • Agent builders and frontier engineers
  • Computational biologists and bioinformaticians
  • Research engineers with a product sensibility
Apply now